| 摘要 |
<p>A method for protecting prostheses and temporarily or permanently implantable materials from bacterial colonisation and infection, wherein the material is successively impregnated with: (a) a biguanide solution having general formula (I), wherein R1 is an alkyl, aminoalkyl, optionally substituted phenyl, naphthyl or cyano radical, R2 is a hydrogn atom or an alkyl radical and n is an integer from 1-6, with the proviso that the alkyl radicals and portions are linear or branched and contain 1-4 carbon atoms; and (b) a solution of an antibacterial agent which may be gradually redistributed in an aqueous medium; whereafter the material thereby impregnated is dried.</p> |
