发明名称 |
Method of treating muscular tension, muscle spasticity and anxiety with 3-aryloxy and 3-arylthioazetidinecarboxamides |
摘要 |
A method of treating animals to obtain muscle relaxation and/or to relieve anxiety is disclosed utilizing novel and known 3-aryloxy and 3-arylthioazetidinecarboxamides having the formula: <IMAGE> wherein Z is oxygen or sulfur; B is oxygen or sulfur; Ar is pyridyl or halo substituted pyridyl, phenyl or substituted phenyl; R1 and R2 are hydrogen, loweralkyl, aryl, allyl groups, propargyl, cycloalkyl, loweralkylcycloalkyl, cycloalkylloweralkyl, arylloweralkyl and diloweralkylaminoalkyl, and R1 and R2 when taken together with the adjacent nitrogen atom may form a heterocyclic amine radical; R3 is hydrogen, loweralkyl, aryl or arylloweralkyl, and the geometrical isomers thereof and pharmaceutical salts thereof and hydrates thereof when they are possible.
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申请公布号 |
US5183902(A) |
申请公布日期 |
1993.02.02 |
申请号 |
US19910743059 |
申请日期 |
1991.08.09 |
申请人 |
A. H. ROBINS COMPANY, INCORPORATED |
发明人 |
TAYLOR, JR., CHANDLER R.;CALE, JR., ALBERT D.;STAUFFER, JR., HAROLD F. |
分类号 |
A61K31/395;A61K31/415;A61K31/44;A61K31/495;C07D205/04;C07D401/12;C07D521/00 |
主分类号 |
A61K31/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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