摘要 |
The compounds of the formula: <IMAGE> wherein X, Y and Z are, independently, hydrogen, halogen, hydroxy, nitro, cyano, carboxyl, trifluoromethyl, phenyl, amino, mono and dialkylamino, C1-C12 alkyl or C1-C12 alkoxy; R1 represents hydrogen, C1-C18 saturated or unsaturated alkyl, cycloalkyl, phenyl, benzyl or substituted phenyl or substituted benzyl where the substituents are C1-C12 alkyl, or C1-C12 alkoxy; R2 represents a substituted thienyl group where the substituents are, independently, the same as X, Y and Z; or a pharmaceutically acceptable salt thereof, are ACAT inhibitors.
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