发明名称 N-phenyl-N'-thienylmethyl-bis-diamino-5-methylene-1,3-dioxane-4,6-dione compounds
摘要 The compounds of the formula: <IMAGE> wherein X, Y and Z are, independently, hydrogen, halogen, hydroxy, nitro, cyano, carboxyl, trifluoromethyl, phenyl, amino, mono and dialkylamino, C1-C12 alkyl or C1-C12 alkoxy; R1 represents hydrogen, C1-C18 saturated or unsaturated alkyl, cycloalkyl, phenyl, benzyl or substituted phenyl or substituted benzyl where the substituents are C1-C12 alkyl, or C1-C12 alkoxy; R2 represents a substituted thienyl group where the substituents are, independently, the same as X, Y and Z; or a pharmaceutically acceptable salt thereof, are ACAT inhibitors.
申请公布号 US5177219(A) 申请公布日期 1993.01.05
申请号 US19920847127 申请日期 1992.03.06
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 FOBARE, WILLIAM F.;STRIKE, DONALD P.
分类号 C07D319/06;C07D333/20;C07D405/12;C07D409/12 主分类号 C07D319/06
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