| 摘要 |
<p>The present invention relates to a compound of general formula (I) wherein R1a is hydrogen atom or an amino-protecting group; R1b is a C1-C4 alkyl group or a group of formula (a) wherein R3 and R4, being the same or different from each other, are hydrogen atom or a C1-C4 alkyl group and R5 is hydrogen atom, an alkali metal or a carboxyl-protecting group; R2 is a C1-C4 alkyl group or a C1-C4 alkyl group substituted by a carboxyl group, an amino group or a hydroxyl group; and Q is carbon or nitrogen atom, and a pharmaceutically acceptable salt thereof. The cephalosporin compound according to the present invention shows potent antimicrobial activity and broad antibacterial spectrum against both gram-negative and gram-positive strains. Thus, the compounds are expected to be very useful for treating the intractable infectious diseases caused by these microorganisms.</p> |
