<p>There is disclosed a calcitonin derivative and its salt, comprising an amino acid residue at the 1-position of calcitonin which is a cyclic amino acid residue represented by the formula: <CHEM> wherein X represents a sulfur atom or a methylene group; and n represents an integer of 0 or 1. and an amino acid residue at the 7-position which is a cysteine residue which may be substituted with an appropriate protective group.</p>
申请公布号
EP0298474(B1)
申请公布日期
1992.11.19
申请号
EP19880110864
申请日期
1988.07.07
申请人
MITSUBISHI PETROCHEMICAL CO., LTD.
发明人
HIROSE, SACHIO MITSUBISHI PETROCHEMICAL CO., LTD.;HANE, MOTOMU CENTRAL RESEARCH LABORATORIES;INAGAWA, NASANOBU CENTRAL RESEARCH LABORATORIES