摘要 |
For inhibiting HMG-CoA reductase and cholesterol synthesis, the novel 2-pyridones and pyrid-2-thiones of the formula <IMAGE> in which A is optionally substituted aryl or heterocyclic, B is optionally substituted alkyl, cycloalkyl or aryl, D and E independently are optionally substituted aryl or heterocyclic, H, nitro, cyano, optionally substituted alkyl, alkenyl or imino, amino, alkoxy or acyl, or forms a ring with B, G is O or S, X is -CH2-CH2- or -CH=CH-, and R represents a group of the formula <IMAGE> and salts thereof.
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申请人 |
BAYER AKTIENGESELLSCHAFT |
发明人 |
FEY, PETER;ANGERBAUER, ROLF;HUEBSCH, WALTER;PHILIPPS, THOMAS;BISCHOFF, HILMAR;PETZINNA, DIETER;SCHMIDT, DELF;THOMAS, GUENTER |