PROCESS FOR PRODUCING A MONOCYTE CHEMOTACTIC FACTOR POLYPEPTIDE AND A STRAIN FOR THE PRODUCTION THEREOF

摘要

A process for producing a monocyte chemotactic factor which comprises constructing an expression plasmid in which has been inserted DNA encoding a monocyte chemotactic factor consisting of 76 amino acids or a polypeptide which has truncated N-terminal amino acids thereof and having a terminator sequence inserted downstream of said DNA, introducing the expression plasmid into a selected E. coli such as an E. coli LE392 strain or the like to transform said E. coli, and cultivating the transformed E. coli.