发明名称 Diol-containing renin inhibitors
摘要 The invention concerns novel renin-inhibitory peptides which are useful for treating renin-associated hypertension, congestive heart failure, hyperaldosteronism, and diseases caused by retroviruses including HTLV-I and -III. Processes for preparing the peptides, compositions containing them, and methods of using them are included. Also included is a diagnostic method which uses the compounds to determine the presence of renin-associated hypertension, or hyperaldosteronism.
申请公布号 PH26816(A) 申请公布日期 1992.11.05
申请号 PH19980000386 申请日期 1989.05.25
申请人 WARNER-LAMBERT COMPANY 发明人 RICHARD HIMMELSBACH;JOHN COOKE HODGES;JAMES STANLEY KALTENBRONN;JOSEPH THOMAS REPINE;ILA SIRCAR;WILLIAM CHESTER PATT
分类号 A61K31/16;A61K31/18;A61K31/27;A61K31/40;A61K31/445;A61K31/495;A61K31/535;A61K31/5375;A61K38/00;A61K38/55;A61P5/38;A61P9/00;A61P9/12;A61P43/00;C07D207/16;C07D233/54;C07D295/18;C07D295/22;C07D333/34;C07K1/02;C07K1/113;C07K5/06;C07K5/065;C07K5/08;C07K14/81 主分类号 A61K31/16
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