HETEROCYCLY1-2-PROPYN-1-AMINES

摘要

This invention relates to novel heterocyclyl-2-propyn-1-amines of the formula Het-C ? C-CH2-NH2 wherein Het is 2- or 3-thienyl or 2- or 3-furyl, each Het ring optionally being substituted with from 1 to 3 moieties selected from the group consisting of lower alkyl of from one to about six carbon atoms, alkoxy of from 1 to about 6 carbon atoms, alkylthio of from 1 to about 6 carbon atoms, fluoro, bromo, chloro, carboxylic acid and hydroxymethyl and the pharmaceutically acceptable acid addition salts thereof, which are useful as dopamine beta hydroxylase inhibitors in the treatment of hypertension.