| 发明名称 |
PROCESSO PARA A PREPARACAO DE PEPTIOLIDOS CICLICO |
| 摘要 |
Cyclic peptolides having the structure of a cyclosporin in which one amide linkage is replaced by an ester linkage are obtained by fermentation of fungal strains of the genus Cylindrotrichum Bonorden, or by cyclisation of a hydroxy-undecapeptide. The cyclic peptolides have immunosuppressive, anti-inflammatory and anti-parasitic properties. |
| 申请公布号 |
PT87763(B) |
申请公布日期 |
1992.10.30 |
| 申请号 |
PT19880087763 |
申请日期 |
1988.06.17 |
| 申请人 |
SANDOZ SA. |
发明人 |
ROLAND WENGER;MICHAEL MORRIS DREYFUSS;HANS TSCHERTER;ALEXANDER HASLBERGER |
| 分类号 |
A61K;A61K38/00;A61P29/00;A61P37/06;C07K;C07K1/02;C07K1/113;C07K11/02;C07K14/37;C07K14/41;C12N;C12N1/14;C12P;C12P21/04;C12R;C12R1/645 |
主分类号 |
A61K |
| 代理机构 |
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代理人 |
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| 地址 |
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