PHARMACEUTICAL PREPARATION FOR EMBEDDING IN BONE

摘要

PURPOSE:To provide the title pharmaceutical preparation capable of supplementing bone tissue repair while sustainedly releasing a medicine. CONSTITUTION:The objective pharmaceutical preparation can be obtained by mixing (A) an artificial bone component with (B) a molded product formed by either compressing a mixture of a medicine with polymeric material or solidification after melting said mixture. Said medicine is e.g. one of various kinds of antibiotics and antineoplastic agents; while said artificial bone component is e.g. hydroxyapatite. Said polymeric material is pref. a biodegradable substance. The release of the medicine from the present pharmaceutical preparation can easily be controlled. Furthermore, after once embedded in the bone, the present pharmaceutical preparation need not be taken out.