发明名称 Use of 4-amino-1-(2-pyridyl)piperidines as 5-HT3-agonists for the treatment and prophylaxis of serotoninergic dysfunctions.
摘要 <p>The subject of the present invention is the use of 4-amino-1-(2-pyridyl)piperidines of general formula (I') &lt;IMAGE&gt; in which R' represents hydrogen, a halogen atom, a methyl, trifluoromethyl, (C1-C3)alkoxy, trifluoromethoxy, 2,2,2-trifluoroethoxy, methylthio, trifluoromethylthio or phenoxy group which is optionally substituted by a halogen, a (C1-C3)alkyl, (C1-C3)alkoxy, (C1-C3)alkylthio, trifluoromethyl or cyano group, or one of its pharmaceutically acceptable salts, for the preparation of a medicinal product for the treatment and prophylaxis of conditions arising from a dysfunction of the serotoninergic systems in which a serotoninergic action, selectively mediated by 5-HT3 receptors, is required.</p>
申请公布号 EP0506545(A2) 申请公布日期 1992.09.30
申请号 EP19920400792 申请日期 1992.03.24
申请人 ELF SANOFI;MIDY S.P.A. 发明人 LE FUR, GERARD;BIANCHETTI, ALBERTO;GIUDICE, ANTONINA;CROCT, TIZIANO;SOUBRIE, PHILIPPE
分类号 C07D401/04;A61K31/44;A61K31/4427;A61K31/445;A61P1/00;A61P1/10;A61P25/00;A61P25/18;A61P25/20;A61P43/00 主分类号 C07D401/04
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