发明名称 Antidepressants
摘要 The present invention provides novel aryloxy indanamines of the formula <IMAGE> wherein n, p and q are each independently 0, 1 or 2, Y and X are each independently lower alkyl, lower alkoxy, hydroxy, CF3, halogeno or when p or q are 2 and each of the Y or each of the X groups are on adjacent aryl carbon atoms, both of the X or both of the Y groups can be taken together to form a methylenedioxy moiety, R1 and R2 are each independently hydrogen, lower alkyl, aralkyl, or R1 and R2 taken together with the nitrogen to which they are attached are pyrrolidino, morpholino, piperidino, piperazino, or 4-methylpiperazino, or an acid addition salt thereof, which are useful as antidepressants and as inhibitors of synaptic norepinephrine and serotonin uptake.
申请公布号 US5149714(A) 申请公布日期 1992.09.22
申请号 US19900569259 申请日期 1990.08.15
申请人 MERRELL DOW PHARMACEUTICALS INC. 发明人 FREEDMAN, JULES
分类号 A61K31/275;A61K31/44;A61K31/495;A61K31/55;C07D295/096 主分类号 A61K31/275
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