发明名称 |
PCTD plasmid isolated form chlamydia trachomatis serotype D, its genes and proteins encoded by them; recombinant plasmids for the expression of said genes in heterologous systems as fused recombinant proteins, preparation of said recombinant proteins and their use in the formulation of vaccins and/or gianostics. |
摘要 |
<p>A plasmid isolated from Clamydia trachomatis is described, which comprises 8 genes encoding proteins useful in the formulation of vaccines or diagnostic test for determining the bacterium or specific antibodies generated during C. trachomatis infections; in particular the recombinant fusion MS2-pgp3D protein is described comprising polypeptidic sequences encoded by pCT and immunogenic in the course of infections in man. A method for preparing said protein in E.coli further described.</p> |
申请公布号 |
EP0499681(A1) |
申请公布日期 |
1992.08.26 |
申请号 |
EP19910106110 |
申请日期 |
1991.04.17 |
申请人 |
SCLAVO S.P.A. |
发明人 |
RATTI, GIULIO;COMANDUCCI, MAURIZIO;TECCE, MARIO F.;GIULIANI, MARZIA M. |
分类号 |
A61K38/00;A61K39/00;C07K14/295;C07K16/12;C12N15/30;C12N15/74 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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