发明名称 |
GM-CSF inhibiting antibodies. |
摘要 |
<p>Provided are antibodies which are capable of inhibiting the biological activity of a granulocyte-macrophage colony stimulating factor ("GM-CSF"). These antibodies are useful for alleviating undesirable biological effects mediated by GM-CSF. In particular, the antibodies are useful for inhibiting the growth of a GM-CSF dependent neoplastic disease. Also provided are formulations and methods for using the antibodies of the invention.</p> |
申请公布号 |
EP0499161(A2) |
申请公布日期 |
1992.08.19 |
申请号 |
EP19920102103 |
申请日期 |
1992.02.07 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
BURSUKER, ISIA;GREENFIELD, ROBERT S.;BRASLAWSKY, GARY R. |
分类号 |
A61K39/395;A61K38/00;A61P29/00;A61P35/00;A61P37/06;C07K7/06;C07K7/08;C07K14/52;C07K14/53;C07K14/535;C07K16/00;C07K16/24;C12N5/10;C12N5/20;C12N15/02;C12P21/08;C12R1/91 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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