A hybrid gene vector suitable for introducing foreign DNA into a mammalian cell comprising the foreign DNA ligated to an AAV genome; a method of constructing the hybrid gene vector; a method of transducing foreign DNA into mammalian cells comprising infecting the cells with the above hybrid gene vector and a method of rescuing foreign DNA from mammalian cells utilizing helper virus.
申请公布号
US5139941(A)
申请公布日期
1992.08.18
申请号
US19910785224
申请日期
1991.10.25
申请人
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
发明人
MUZYCZKA, NICHOLAS;HERMONAT, PAUL L.;BERNS, KENNETH I.;SAMULSKI, RICHARD J.