发明名称 ANALYSIS SYSTEM AND METHOD FOR THE DETERMINATION OF AN ANALYTE IN A LIQUID SAMPLE
摘要 <p>Analysis system for determining an analyte in a liquid sample, in particular a body fluid, by means of a specific binding reaction between two bioaffinic binding partners, one of which is substrate-immobilised and the other is free. The system comprises analysis elements (10) in whose test region (13) the substrate-immobilised binding partner is immobilised and an evaluation instrument (1) embodying an optical reflection measuring device for detecting the change in layer thickness resulting from the binding of the free binding partner to the substrate-immobilised binding partner. An increase in the measurement accuracy is achieved if the test region (13) has spatially separated subregions (14, 15) having varying binding activities of the substrate-immobilised binding partner and the optical reflection measuring device detects the subregions (14, 15) in a spatially differentiated manner, the measured values obtained from the subregions (14, 15) being compared with one another. <IMAGE></p>
申请公布号 EP0469377(A3) 申请公布日期 1992.08.12
申请号 EP19910111830 申请日期 1991.07.16
申请人 BOEHRINGER MANNHEIM GMBH 发明人 KNOLL, WOLFGANG;SCHMITT, FRANZ-JOSEF
分类号 G01N21/47;G01N21/27;G01N21/552;G01N33/543;(IPC1-7):G01N33/543 主分类号 G01N21/47
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