| 摘要 |
Compounds of formula I A &lsqbstr& X - Y]n I wherein A is a chelating group capable of complexing a detectable element, n is 1 or 2 X is a direct bond or a spacer group, and Y is a residue derived from a alpha -or beta -MSH peptide bearing in the 10- or 11-position a substituted side chain group A-X being linked to the terminal amino group of the peptide residue Y and the substitution on the side chain group in the 10- or 11-position being selected so that it does not significantly interfere with or impair the binding affinity of the peptide to the MSH receptors, in free form or in a salt form are useful when labelled with a detectable element in in vivo diagnostic and therapeutic applications.
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