发明名称 |
STABLE SOLVENT ADDUCTS OF Z-1-(P-.beta.- DIMETHYLAMINOETHOXY-PHENYL)-1-(P-HYDROXYPHENYL)-2- PHENYL-BUT-1-ENE |
摘要 |
This invention relates to new stereochemically pure and stable adducts of Z-1-(p-.beta.-dimethylaminoetlloxyl)henyl)-1- (p-hydroxyphenyl)-2-phenyl-but-1-ene and certain solvents which by virtue of their marked antioestrogenic activities may be used for the therapeutic treatment of benign breast diseases and hormone-dependent mammary tumours, in particular by percutaneous application. |
申请公布号 |
CA1305972(C) |
申请公布日期 |
1992.08.04 |
申请号 |
CA19880562434 |
申请日期 |
1988.03.25 |
申请人 |
HEUMANN PHARMA GMBH & CO |
发明人 |
GRAFE, INGOMAR;SCHICKANEDER, HELMUT;JUNGBLUT, PETER W.;AHRENS, KURT H. |
分类号 |
A61K31/135;A61P35/00;C07C67/00;C07C213/00;C07C213/02;C07C217/16;C07C217/20 |
主分类号 |
A61K31/135 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|