发明名称 STABLE SOLVENT ADDUCTS OF Z-1-(P-.beta.- DIMETHYLAMINOETHOXY-PHENYL)-1-(P-HYDROXYPHENYL)-2- PHENYL-BUT-1-ENE
摘要 This invention relates to new stereochemically pure and stable adducts of Z-1-(p-.beta.-dimethylaminoetlloxyl)henyl)-1- (p-hydroxyphenyl)-2-phenyl-but-1-ene and certain solvents which by virtue of their marked antioestrogenic activities may be used for the therapeutic treatment of benign breast diseases and hormone-dependent mammary tumours, in particular by percutaneous application.
申请公布号 CA1305972(C) 申请公布日期 1992.08.04
申请号 CA19880562434 申请日期 1988.03.25
申请人 HEUMANN PHARMA GMBH & CO 发明人 GRAFE, INGOMAR;SCHICKANEDER, HELMUT;JUNGBLUT, PETER W.;AHRENS, KURT H.
分类号 A61K31/135;A61P35/00;C07C67/00;C07C213/00;C07C213/02;C07C217/16;C07C217/20 主分类号 A61K31/135
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