23-OXA-DERIVATE IN DER VITAMIN-D-REIHE, VERFAHREN ZU IHRER HERSTELLUNG DIESE DERIVATE ENTHALTENDE PHARMAZEUTISCHE PRAEPARATE SOWIE DEREN VERWENDUNG ALS ARZNEIMITTEL

摘要

The invention concerns 23-oxa derivatives of vitamins of the D-series, the derivatives having the formula (I), in which R<1>, R<2> and R<4>, independently of each other, may be a hydrogen atom or an acyl group with 1-9 carbon atoms; each R<3> may be a hydrogen atom or a straight-chain or branched-chain alkyl group with 1-4 carbon atoms; and x is an alkylene residue-(CH2)n-in which n =1, 2 or 3, neither of the R<3> groups being methyl or propyl when n = 1. The invention also concerns a method of preparing such derivatives. The compounds have a proliferation inhibiting and cell differentiating effect and are suitable for the production of medicaments.