摘要 |
<p>A synthetic vaccine comprises a recombinant vaccine vector that incorporates a nucleotide sequence capable of being expressed as all or part of an HIV reverse transcriptase. The vector is combined with all or part of a purified HIV reverse transcriptase in an adjuvant. The vaccine vectors include poxvirus, herpes virus, and adenovirus. The synthetic vaccine applies particularly to the augmentation of immune responses in HIV-infected asymptomatic, immunosuppressed, or immunodeficient animals or humans.</p> |