发明名称 |
4-AZATRICYCLO[2.2.1.0<2,6>]HEPTANES AND PHARMACEUTICAL COMPOSITIONS |
摘要 |
4-Azatricyclo[2.2.1.0<2,6>]heptanes, formula (I) or salts or prodrugs thereof, where R' is an amide, ester, oxime ether or a 5-membered heterocycle and with a substituent of low lipophilicity, are useful in the treatment of neurological disorders and glaucoma. They may be prepared by methods of or analogous to published syntheses and may be formulated in conventional pharmaceutical compositions for administration. |
申请公布号 |
WO9211261(A1) |
申请公布日期 |
1992.07.09 |
申请号 |
WO1990GB02016 |
申请日期 |
1990.12.21 |
申请人 |
MERCK SHARP & DOHME LIMITED |
发明人 |
MACLEOD, ANGUS, M.;HERBERT, RICHARD;HOOGSTEEN, KARST |
分类号 |
A61K31/40;A61P25/00;A61P25/28;C07D487/08 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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