| 摘要 |
PCT No. PCT/EP89/00376 Sec. 371 Date Oct. 9, 1990 Sec. 102(e) Date Oct. 9, 1990 PCT Filed Apr. 6, 1989 PCT Pub. No. WO89/09625 PCT Pub. Date Oct. 19, 1989.There is provided a method of generating enhanced images of the human or non-human animal body, for example for use in medical diagnosis, which involves administering to the body a positive MRI contrast agent which is body tissue- or body duct-specific following the particular mode of administration and a negative MRI contrast agent which preferably also is body tissue- or body duct-specific. Thereafter a magnetic resonance image is generated of a part of the body containing the negative and positive contrast agents or their paramagnetic, ferromagnetic or superparamagnetic biodegradation products. Contrast media suitable for use in this new image generating method are also provided.
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