The invention relates to a process of recovery of natamycin from a fermentation broth containing at least 2 g/l natamycin by adding methanol and adjusting the pH to 1.0 to 4.5 to dissolve the precipitated natamycin; removing the remaining suspended solids; and raising the pH to 6.0 to 9.0 to precipitate high purity natamycin.
申请公布号
WO9210580(A1)
申请公布日期
1992.06.25
申请号
WO1991US08931
申请日期
1991.12.05
申请人
E.I. DU PONT DE NEMOURS AND COMPANY
发明人
MILLIS, JAMES, R.;OLSON, PHILLIP, TERRY;REIMER, MICHAEL, HENRY