| 摘要 |
<p>Antimicrobial quinolonyl lactam compounds comprising a lactam-containing moiety linked, by a non-ester linking moiety, to the 3-carboxy group of a quinolone moiety. These compounds are of the formula: <CHEM> wherein (1) R<3>, R<4>, and R<5>, together with bonds "a" and "b", form any of a variety of lactam-containing moieties similar to those known in the art to have antimicrobial activity; (2) A, R<6>, R<7>, and R<8> form any of a variety of quinolone or naphthyridine structures similar to those known in the art to have antimicrobial activity; and (3) Y, together with R<5>, form a variety of non-ester linking moieties between the lactam-containing moiety and the quinolone moiety. c</p> |
