发明名称 META-SUBSTITUTED PHENYL ALANINE DERIVATIVES
摘要 PCT No. PCT/CH91/00235 Sec. 371 Date Feb. 10, 1993 Sec. 102(e) Date Feb. 10, 1993 PCT Filed Nov. 15, 1991 PCT Pub. No. WO92/08709 PCT Pub. Date Mar. 29, 1992.D,L-, L- and D-phenyl alanine derivatives of formula (I) defined in claim 1 in which R1 is an amidino-, guanidino-, oxamidino-, aminomethyl- or amino group have been discovered which effectively prevent blood coagulation or thrombosis. The antithrombotically active compounds have low toxicity and may be administered by mouth, subcutaneously or intravenously.
申请公布号 AU8868991(A) 申请公布日期 1992.06.11
申请号 AU19910088689 申请日期 1991.11.15
申请人 PENTAPHARM AG 发明人 JORG STURZEBECHER;HELMUT VIEWEG;PETER WIKSTROEM
分类号 A61K31/195;A61K31/198;A61K31/215;A61K31/4427;A61K31/445;A61K31/495;A61K38/00;A61P43/00;C07C311/19;C07C327/58;C07D211/16;C07D211/60;C07D211/62;C07D215/36;C07D215/50;C07D217/26;C07D295/10;C07D295/185;C07D401/12;C07K5/02;C07K5/06;C07K5/068;C07K5/08;C07K5/083;C07K5/09;C07K14/81 主分类号 A61K31/195
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