发明名称 Covalently linked polypeptide cell modulators such as interferon-lymphotoxin conjugates
摘要 Described is a new class of polypeptide cell modulators characterized by being composed of two covalently linked cell modulators in a linear polypeptide sequence. Such dual function polypeptides have new and particularly useful activities when the component polypeptide cell modulators are interferons, lymphokines or cytotoxins which act through different and specific cell receptors to initiate complementary biological activities.
申请公布号 US5114711(A) 申请公布日期 1992.05.19
申请号 US19890379509 申请日期 1989.07.13
申请人 G. D. SEARLE & CO. 发明人 BELL, LESLIE D.;MCCULLAGH, KEITH G.;PORTER, ALAN G.
分类号 C12N15/09;A61K38/00;A61K38/21;A61K38/22;A61P31/12;A61P35/00;A61P37/00;C07H21/04;C07K14/00;C07K14/475;C07K14/52;C07K14/525;C07K14/54;C07K14/555;C07K14/565;C07K14/57;C07K19/00;C12N1/21;C12N15/00;C12N15/62;C12N15/70;C12P21/00;C12P21/02;C12R1/19 主分类号 C12N15/09
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