| 摘要 |
21-Mercapto-steroids of the pregnane series of the general formula WHEREIN R1 = H or an acyl radical R2 = H or free or esterified hydroxyl R3 = CH3 or alpha -hydroxy, free or esterified OR R2 + R3 = alkylidene or cycloalkylidene dihydroxy R4 = Cl or free or esterified hydroxy R5 = H or R4 + R5 = oxo R6 = H, Cl or F or R4 + R6 = a double bond or an epoxy group R7 = H or, if a double bond in 1,2-position is present, ALSO Cl, e.g., the 6 alpha ,9 alpha -difluoro-2-chloro-16 alpha -methyl-11 beta ,17 alpha -dihydroxy-21-acetyl-mercapto-pregna-1,4-diene-3,20-dione. Use: antiinflammating agents. |
