| 摘要 |
<p>In reaction vessels which are used for PCR (polymerase chain reaction) amplification, there is a risk of leakage of amplified DNA into the atmosphere if the vessel is not thoroughly sealed. One particular area through which amplified DNA can leak is the access port through which the sample is introduced into the vessel. Described herein is a lockable valve mechanism (10) for introducing a liquid sample into an associated reaction vessel (12) which can be sealed after the sample has been introduced. the mechanism (10) includes a valve body (16), and a valve member (18) rotatably mounted thereon. The valve member (18) is movable from an open position, wherein an inlet passage (34) formed in the valve member is aligned with an outlet passage (22) of the valve body (16) for introduction of a sample into the reaction vessel (12), to a closed and sealed position, wherein the outlet passage (22) of the valve body (16) is sealed. The valve member (18) includes a locking mechanism (28, 38) to prevent movement of the valve member (18) out of the closed and sealed position after movement from the open position into the sealed position. <IMAGE></p> |
