摘要 |
PCT No. PCT/GB90/01279 Sec. 371 Date Feb. 6, 1992 Sec. 102(e) Date Feb. 6, 1992 PCT Filed Aug. 14, 1990 PCT Pub. No. WO91/02763 PCT Pub. Date Mar. 7, 1991.Linear chain extended poly(alkylene oxides) having at least a portion of hydrophobic hydrogen bonding chain extending groups are soluble in at least one solvent and swellable in water. The chain extending groups preferably comprise a urea linkage and can be produced by the reaction of an amine with an isocyanate. The extended polymers and their solutions may readily be fabricated into controlled release compositions, e.g. for the release of pharmaceuticals. |