发明名称 1-(PYRIDINYLALKYL)-1H-INDOLES,INDOLINES AND RELATED ANALOGS
摘要 This invention relates to compounds of the formula <CHEM> wherein R1 is hydrogen, loweralkyl, arylloweralkyl, loweralkenyl or loweralkynyl; R2 is hydrogen, lowralkyl, loweralkenyl, formyl or cyano; X is hydrogen, halogen, nitro, amino, loweralkyl, loweralkoxy or hydroxy; Y is hydrogen, loweralkyl, loweralkoxy, arylloweralkoxy, hydroxy, halogen, nitro or amino; the pharmaceutically acceptable acid addition salts thereof, and, where applicable, the geometric and optical isomers and racemic mixtures thereof. The compounds of the invention are useful for the treatment of various memory dysfunctions characterized by a decreased cholinergic function, such as Alzheimer's disease.
申请公布号 ZA9106341(B) 申请公布日期 1992.04.29
申请号 ZA19910006341 申请日期 1991.08.12
申请人 HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED 发明人 RICHARD CHARLES EFFLAND;LARRY DAVIS;GORDON EDWARD OLSEN
分类号 A61K31/41;A61K31/44;A61K31/4427;A61K31/4439;A61P25/28;C07D401/06 主分类号 A61K31/41
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