发明名称 |
Prodrugs of phosphonates. |
摘要 |
<p>There are disclosed novel oral prodrugs of phosphonate nucleotide analogs which are hydrolyzable under physiological conditions to yield compounds which are useful as antiviral agents, especially as agents effective against RNA and DNA viruses. They may also find use as antitumor agents.</p> |
申请公布号 |
EP0481214(A1) |
申请公布日期 |
1992.04.22 |
申请号 |
EP19910115312 |
申请日期 |
1991.09.10 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
STARRETT, JOHN EDWARD, JR.;MANSURI, MUZAMMIL M.;MARTIN, JOHN C.;TORTOLANI, DAVID R.;BRONSON, JOANNE J. |
分类号 |
A61P31/12;A61K31/675;A61K31/66;A61K31/70;A61P35/00;C07F9/6512;C07F9/6561;C07F9/6571;C07F9/6574;C07F9/6584;C07H13/10;C07H19/10;C07H19/20;(IPC1-7):C07F9/656;C07F9/651;C07F9/657;C07F9/658 |
主分类号 |
A61P31/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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