发明名称 NUOVI DERIVATI BASICI DELL'ACIDO GLUTAMMICO ED ACIDO ASPARTICO, PROCE-DIMENTO PER LA LORO PREPARAZIONE E LORO USO FARMACEUTICO.
摘要 PCT No. PCT/EP93/00842 Sec. 371 Date Oct. 11, 1994 Sec. 102(e) Date Oct. 11, 1994 PCT Filed Apr. 6, 1993 PCT Pub. No. WO93/21172 PCT Pub. Date Oct. 28, 1993Compounds of general formula (I), in which r is 1 or 2, R1 is selected independently from: unsubstituted, mono- or di-substituted phenyl groups, unsubstituted, mono- or di-substituted phenylamino groups, the 2(beta)-naphthyl group, and heterocyclic, monocyclic or dicyclic groups; R2 is selected independently from: heterocyclic spiro groups, aminoalkyladamantyl groups, alkylamino groups, C4-C10 cycloalkylamino groups, and dicyclic amino groups (condensed); R3 is H, CH3 or C2H5; A is a bond or a linear or branched alkylene group comprising from 1 to 4 carbon atoms; W is a tertiary amino group or a heterocyclic group.
申请公布号 ITTO920325(D0) 申请公布日期 1992.04.09
申请号 IT1992TO00325 申请日期 1992.04.09
申请人 ROTTA RESEARCH LABORATORIUM S.P.A. 发明人 MAKOVEC FRANCESCO;ROVATI LUCIO;ROVATI LUIGI
分类号 C07D295/12;A61K31/40;A61K31/435;A61K31/4427;A61K31/443;A61K31/445;A61K31/47;A61K31/472;A61K31/495;A61K31/535;A61K31/5375;A61P1/00;A61P1/04;A61P1/16;A61P1/18;A61P13/02;A61P13/06;A61P15/00;A61P25/00;A61P25/22;A61P27/02;A61P27/12;A61P43/00;C07C237/22;C07D207/09;C07D207/14;C07D215/54;C07D217/06;C07D221/20;C07D295/13;C07D295/18;C07D295/185;C07D401/12;C07D405/12;C07D453/02 主分类号 C07D295/12
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