| 发明名称 |
URACIL REDUCTASE INACTIVATORS |
| 摘要 |
Uracil reductase inactivators, notably a 5-substituted uracil or 5,6-dihydro -5-substituted uracil, potentiate 5-fluorouracil and find use particularly in the treatment of cancer. The 5-substituent is selected from bromo, iodo, cyano, halo-substituted C1-4 alkyl, C2-6 alkenyl, 1-halo- C2-6 alkenyl and halo-substituted C2-6 alkynyl. |
| 申请公布号 |
WO9204901(A1) |
申请公布日期 |
1992.04.02 |
| 申请号 |
WO1991GB01650 |
申请日期 |
1991.09.25 |
| 申请人 |
THE WELLCOME FOUNDATION LIMITED |
发明人 |
SPECTOR, THOMAS;PORTER, DAVID, JOHN, TIMOTHY;RAHIM, SAAD, GEORGE |
| 分类号 |
A61K31/7105;A61K;A61K31/505;A61K31/513;A61K31/70;A61K45/00;A61K45/06;A61P35/00;C07D239/54;C07H19/06 |
主分类号 |
A61K31/7105 |
| 代理机构 |
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