<p>An antiviral agent produced by Hypoxylon fragiforme and having the structure: <CHEM> is described. The product has high activity as an HIV protease enzyme inhibitor and is useful in the treatment of diseases in which control of HIV protease activity is desirable.</p>
申请公布号
EP0478061(A1)
申请公布日期
1992.04.01
申请号
EP19910202395
申请日期
1991.09.18
申请人
MERCK & CO. INC.
发明人
BILLS, GERALD F.;ONDEYKA, JOHN G.;HENSENS, OTTO D.;ZINK, DEBORAH L.;KOUPAL, LAWRENCE;LINGHAM, RUSSELL B.
