BENZHYDRYLPIPERAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME

摘要

BENZHYDRYLPIPERAZINE DERIVATIVES, PHARMACEUTICAL COMPO SITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME The invention relates to novel benzhydrylpiperazine derivatives of the general formula (I) and the acid addition and quaternary ammonium salts thereof, pharmaceutical compositions containing them and a process for their preparation. In the general formula (I) (I) R1, R2, R3, R4 and R5 are the same or different and stand for hydrogen or halogen, or a trihalomethyl, C1-4 alkyl or C1-4 alkoxy group; R6 means hydrogen or a C1-4 alkyl group; and n is 2 or 3. The compounds of the general formula (I) are useful for treating diseases arising from a decrease in the dopamine level, i.e. from a hypofunction of the dopaminergic system, and have low toxicity.