发明名称 |
3-Aryl-4(3H)quinazolinone CCK antagonists and pharmaceutical formulations thereof. |
摘要 |
<p>Novel substituted quinazolinones have been found to exhibit specific binding to cholecystokinin (CCK) receptors in the brain and/or peripheral site such as the pancreas and ileum. The quinazolinones are CCK receptor antagonists and find therapeutic application in the treatment of gastrointestinal disorders and central nervous system disorders, and are useful for appetite regulation in mammals. Pharmaceutical formulations for such indications are described.</p> |
申请公布号 |
EP0475755(A1) |
申请公布日期 |
1992.03.18 |
申请号 |
EP19910308324 |
申请日期 |
1991.09.12 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
MCCOWAN, JEFFERSON RAY;THRASHER, KENNETH JEFF;YU, MELVIN JOSEPH |
分类号 |
A61K31/505;A61P1/00;A61P3/04;A61P25/00;C07D209/14;C07D239/91;C07D403/06 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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