COMPOSITIONS FOR THE SUSTAINED-RELEASE OF CHLORHEXIDINE

摘要

Biodegradable sustained-release compositions capable of achieving the sustained release of chlorhexidine, comprise chlorhexidine digluconate, a protein such as gelatin (which may be cross-linked) and optionally a plasticiser such as glycerin. The compositions can be formed into implant devices which may be used to treat a wide variety of diseases and conditions. The implants are especially useful in treating disease such as periodontal disease which require prolonged drug release.