| 摘要 |
PURPOSE:A microorganism in Brevibacterium or Corynebacterium, which resists a compound with vitamin P activity and produces the titled substance, is cultured and the titled substance is collected. CONSTITUTION:A microorganism in Brevibacterium or Corynebacterium, which resists a compound with vitamin P activity such as esculetin, rutin or hesperidin and produces L-histidine, such as Brevibacterium flavum (FERM-P5506) or Corynebacterium acetoacidphilum (FERM-P5507) is aerobically cultured in a usual medium containing carbon source, nitrogen source and inorganic ions and L-histidine is collected from the culture mixture through the ion exchange resin process. |
