RENIN INHIBITORS HAVING ALL RETRO-INVERTED PEPTIDE BONDS

摘要

Renin-inhibiting peptides of the formula <IMAGE> (I) in which X represents a group of the formula <IMAGE> <IMAGE> represents hydroxyl, alkoxy having up to 8 carbon atoms, benzyloxy or a group of the formula -NR4R5, A, B, D and E are identical or different and in each case represent a direct bond, represent a radical of the formula <IMAGE> in which Q1 denotes oxygen, sulphur or the methylene group represent a grouping of the formula <IMAGE> m represents a number 0, 1 or 2, and L represents a group of the formula -CH2NR2R3 and physiologically acceptable salts thereof.