Indenyl hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase

摘要

Compounds having the formula I: <IMAGE> I are inhibitors of the 5-lipoxygenase enzyme. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.