摘要 |
<p>Conjugates of general formula (1): [A-O-W-Z]a-T wherein the moiety A-O- is the residue of drug of formula A-O-H in which -O-H is a primary or secondary hydroxyl group; a is an integer of from 1 to 30; W is a group of general formula (2) wherein b is an integer of from 1 to 4, B represents a C1-C3 alkylene group and R1 and R2 each independently represent hydrogen, halogen, alkyl, phenyl or substituted phenyl; Z is a spacer group and T is a carrier moiety.</p> |