发明名称 NEW LINKER FOR BIOACTIVE AGENTS
摘要 <p>Conjugates of general formula (1): [A-O-W-Z]a-T wherein the moiety A-O- is the residue of drug of formula A-O-H in which -O-H is a primary or secondary hydroxyl group; a is an integer of from 1 to 30; W is a group of general formula (2) wherein b is an integer of from 1 to 4, B represents a C1-C3 alkylene group and R1 and R2 each independently represent hydrogen, halogen, alkyl, phenyl or substituted phenyl; Z is a spacer group and T is a carrier moiety.</p>
申请公布号 WO1992002255(A1) 申请公布日期 1992.02.20
申请号 EP1991001449 申请日期 1991.08.01
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