发明名称 |
PEPTIDES WITH A CHARACTERISTIC ANTIGENIC DETERMINANT FOR ALPHAL-MICROGLOBULIN |
摘要 |
A b s t r a c t A peptide according to the present invention is not more than 40 amino acids long and contains a sequence which is at least 6 amino acids long from the amino acid partial sequence between the amino acids 144 and 183 of human .alpha.1-microglobulin or/and a sequence which is at least 6 amino acids long from the amino acid partial sequence between the amino acids 1 and 20 of human .alpha.1-microglobulin. An antibody according to the present invention is capable of specific binding to a peptide according to the present invention as well as to human .alpha.1-microglobulin. In order to determine human .alpha.1-microglobulin in a sample liquid by an immunoassay, the sample liquid is brought into contact simultaneously or sequentially with defined amounts of the components antibody and peptide whereby one of the components is labelled and the determination is carried out by means of this label.
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申请公布号 |
CA2048305(A1) |
申请公布日期 |
1992.02.07 |
申请号 |
CA19912048305 |
申请日期 |
1991.08.01 |
申请人 |
BOEHRINGER MANNHEIM G.M.B.H. |
发明人 |
KOPETZKI, ERHARD;KLEIN, CHRISTIAN;MANGOLD, DIETER;STOCK, WERNER;SCHLIPFENBACHER, REINER |
分类号 |
A61K39/395;C07K7/06;C07K7/08;C07K14/00;C07K16/00;C07K16/06;C07K16/18;C12N5/10;C12N15/02;C12P21/08;C12R1/91;G01N31/22;G01N33/53;(IPC1-7):C07K7/04;C07K14/47;G01N33/543;G01N33/566 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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