摘要 |
PURPOSE: To obtain a medicine useful for treatment of glaucoma which does not give rise to such local side effects a irritation, inflammation or high blood pressure of eye in local application. CONSTITUTION: The compd. of the formula (X is H conjugated withα-amino group of Arg, a 1 to 4C acyl; Y is OH conjugated with the corbonyl group at position 1 of Asp, a 1 to 4C alkoxy, an amino acid serine residue conjugated by peptide bond) and the pharmaceutically acceptable salt are used for production of the medicine useful for treatment of the glaucoma. this medicine compsn. is prepd. in the form of eyedrops, liquid agent and ointment and especially preferably the eyedrops are adequate. |