BENZIMIDAZOLES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM

摘要

The invention .relates to benzimidazoles of formula I (see formula I) their 1-, 3-isomer mixtures, and the salts thereof, wherein the substituents R1, R2, R3 and R4 are preferably as follows: R1 in the 6-position represents a 1-methylbenzimidazol- 2-yl, 3,4,5,6-tetrahydro-phthalimino, 2,3-diphenyl-maleic acid imido, 2,3-dimethyl-maleic acid imido, N-phenylmethanesulphonyl.-methylamino, 2-oxo-pyrrolidin-1-yl, 2-oxo-piperidin-1-yl, 2-oxo-hexamethyleneimino, 2-oxo-3, 4-tetramethylene-pyrrolidin-2-yl, 3,3-dimethylglutarimido, N-methylaminocarbonyl-n-pentylamino, propanesultam-1-yl or butanesultam-1-yl group; R2 represents a methyl, ethyl, n-propyl or n-butyl group; R3 represents a carboxy or 1H-tetrazolyl group; and R4 represents a hydrogen atom. These compounds have valuable properties, in particular as angiotensin-II antagonists.