发明名称 |
Antibodies that bind M. tuberculosis polypeptides |
摘要 |
Purified antibodies that bind to M. tuberculosis ERP protein are disclosed. In one a embodiment, a purified antibody, which binds specifically with a polypeptide comprising SEQ ID NO: 39 or SEQ ID NO: 41 is provided. In some embodiments the polypeptide has a theoretical molecular weight of about 28 kDa. In other embodiments the polypeptide has an observed molecular weight of about 36 kDa, as determined by denaturing polyacrylamide gel electrophoresis (SDS-PAGE). The purified antibody may be a monoclonal or a polyclonal antibody. Further embodiments provide antibodies that does not bind specifically with M. teprae P28 protein. The antibodies of the invention have many uses including the identification of M. tuberculosis.
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申请公布号 |
US2006127959(A1) |
申请公布日期 |
2006.06.15 |
申请号 |
US20030342232 |
申请日期 |
2003.01.15 |
申请人 |
INSTITUT PASTEUR |
发明人 |
GICQUEL BRIGITTE;LIM ENG M.;PORTNOI DENIS;BERTHET FRANCOIS-XAVIER;TIMM JULIANO |
分类号 |
C12N15/09;G01N33/554;A61K39/00;A61K39/04;A61K39/395;C07K14/35;C07K16/12;C12N1/21;C12N15/00;C12N15/31;C12N15/74;C12P21/02;C12P21/08;C12Q1/68;C12R1/19;C12R1/32;C12R1/34;G01N33/569 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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