| 发明名称 |
CLASS II PROTEIN OF THE OUTER MEMBRANE OF NEISSERIA MENINGITIDIS HAVING IMMUNOLOGIC CARRIER AND ENHANCEMENT PROPERTIES, AND VACCINES CONTAINING SAME |
| 摘要 |
105/GHB25 18159IA TITLE OF THE INVENTION THE CLASS II PROTEIN OF THE OUTER MEMBRANE OF NEISSERIA MENINGITIDIS HAVING IMMUNOLOGIC CARRIER AND ENHANCEMENT PROPERTIES, AND VACCINES CONTAINING SAME The Class II major immuno-enhancing protein (MIEP) of Neisseria meningitidis, purified directly from the outer membrane of Neisseria meningitidis, or obtained through recombinant cloning and expression of DNA encoding the MIEP of Neisseria meningintidis, has immunologic carrier as well as immunologic enhancement and mitogenic properties.
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| 申请公布号 |
CA2050635(A1) |
申请公布日期 |
1992.01.20 |
| 申请号 |
CA19912050635 |
申请日期 |
1991.07.15 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
OLIFF, ALLEN I.;LIU, MARGARET A.;FRIEDMAN, ARTHUR;TAI, JOSEPH Y.;DONNELLY, JOHN J. |
| 分类号 |
A61K39/095;A61K;A61K39/102;A61K39/145;A61K39/21;A61K39/385;A61K39/39;A61K47/42;A61K47/48;A61P31/12;C07K;C07K5/10;C07K7/06;C07K7/08;C12N1/20;C12N15/31;(IPC1-7):A61K47/42 |
主分类号 |
A61K39/095 |
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