| 摘要 |
Anthracycline glycoside derivs. of formula (I) and cpds. of formula (II) are new. In the formulas, R=H or OH; R1 = acetyloxy, benzoyloxy, methane sulfonyl or para-toluene sulfonyloxy; R2=H, acetyl or benzoyl. Also claimed is the prepn. of (I) comprises condensing 2,4,6-trideoxy-3-acetyl-α-L-talopyranosyl chloride (II) with daunomycin, and deacylating the obtd. cpd. with sodium methoxide and methanol; or reacting (II) with 14-hydroxy protected adriamycinone, deacylating the obtd. cpd. with sodium methoxide, and reacting it with tetrabutyl ammonium fluoride.
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