发明名称 |
PHARMACEUTICAL FORMULATION COMPRISING EZETIMIBE |
摘要 |
The present invention relates to novel formulations comprising ezetimibe as active ingredient. In particular the invention relates to a pharmaceutical composition comprising 5 to 20 wt-% ezetimibe, 50 to 85 wt-% diluent, 3 to 25 wt-% disintegrant, 1 to 10 wt-% binder, and 0.5 to 1 wt-% lubricant, characterized in that the ezetimibe has a particle size distribution of d(0.9) of 5 µm to 35 µm and d(0.5) of 3 µm to 20 µm, as well as methods for preparing said formulations. |
申请公布号 |
WO2009074286(A2) |
申请公布日期 |
2009.06.18 |
申请号 |
WO2008EP10431 |
申请日期 |
2008.12.09 |
申请人 |
RATIOPHARM GMBH;GAT, GANESH;GIRIDHARA RAO, PASUPULETI;HUSSAIN, JAVED |
发明人 |
GAT, GANESH;GIRIDHARA RAO, PASUPULETI;HUSSAIN, JAVED |
分类号 |
A61K9/20;A61K31/397 |
主分类号 |
A61K9/20 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|