发明名称 A lipoxygenase inhibitor.
摘要 <p>A lipoxygenase inhibitor composition comprising as active ingredient a lipoxygenase inhibiting effective amount of a substituted styrene derivative having formula &lt;Chemistry id="chema01" num="0001"&gt;&lt;Image id="ia01" he="32" wi="111" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;wherein X represents a hydroxyl group or a lower alkoxy group having 1 to 4 carbon atoms, q is an integer of 2 or 3; and R&lt;Sub&gt;2&lt;/Sub&gt; and R&lt;Sub&gt;3&lt;/Sub&gt; each represents a hydrogen atom, a lower alkoxy group or a hydroxyl group and Z represents a radical of the formula, -O-(CH&lt;Sub&gt;2&lt;/Sub&gt;)&lt;Sub&gt;n&lt;/Sub&gt;-CH=CH-, -NH-(CH&lt;Sub&gt;2&lt;/Sub&gt;)&lt;Sub&gt;n&lt;/Sub&gt;-, wherein n is an integer of 1 to 4, and a pharmaceutically acceptable carrier.</p>
申请公布号 EP0464859(A1) 申请公布日期 1992.01.08
申请号 EP19910111977 申请日期 1985.05.23
申请人 GREEN CROSS CORPORATION 发明人 YOKOYAMA, KAZUMASA;FUKAYA, CHIKARA;SUGIURA, MASANORI;NAITO, YOUICHIRO;NISHIDA, MASAYUKI;SUYAMA, TADAKAZU
分类号 A61K31/05;A61K31/085;A61K31/09;A61K31/12;A61K31/165;A61K31/216;C07C39/19;C07C43/23;C07C45/67;C07C45/72;C07C49/248;C07C49/255;C07C69/732;C07C235/34;C07D309/12 主分类号 A61K31/05
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